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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e060ff159cdacf6db82dda2f1093bbc18507b20889ccaa15d9a7086bee13f83f' 
  AND token = 'EM0GqTfzWOmIM8s6xGCXPngzb6PpCsa7iGQl6+3nN3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}