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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6374f63066def06113aeb5f47275b245212f47011ace8290d89a34f7a57f95da' 
  AND token = 'VkrAGkZXKTw2bIku1WwxOI/KpnP6ipgJCWGrpp3mdSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00008

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}