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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04c4cb0c1e2a166a6569dc8ce2e579b4e6ee57af11e50413f88c833eb0565472' 
  AND token = 'AJ0F2wWJSqSSfRygKV/yGUQjymKR4/6tOkYrJAKZtgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}