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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4c643e5cec1fed2d26e301c490ee7b280dc68af871a3c23862802db1bb4c15f' 
  AND token = '8v5/6z70hlKkrwjJSpf5I0xgfZjbIY/a9+Y2jdDoHy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}