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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b18998f7fe6101326511c4662b28f1801cccee7223b9d191f2191f3c795668f1' 
  AND token = '+Y/PPqdOm+ICGse82cR32UliVhHxHUVmJGEPCqd9jN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}