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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1ccd56a541944b47c860977f7fb5fcaa7adba2e0daadb9e7e6c244c8150430e' 
  AND token = 'cGUJkpoCrHsvn+OwNrIQJHJbDWYnvRfbmTvUQoWfTQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}