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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2d2f1a1fc40d032ff944ad499b515b1282f83d597036d1fec110f871d62735' 
  AND token = 'AkdtkLOqn2X36kpGV0u7AZRhFpJPjNVzG2eNYkGiDhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}