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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a5c068eafd06131edfade382d2df29959557c35c700f448e8bb737984b96178' 
  AND token = 'BnmEmP+XFD6FsL2HnCGeaeFeGATAbI0HJinO684R7AE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}