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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cf480639a6956a844b4bdfa26f96582618abeade5e7b15201f2de1a6779aee1' 
  AND token = 'v37uGLfI+z+2GAN95IIBp6HDuWQ4vUcBcPpV0JWQWz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}