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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c9db80b61f0196cad030037f183d8ed4e9e4105c2c386a2f425b43da4c71edc' 
  AND token = 'qzIrtSacFvpDg75C0LXLkoFj8cz2FvWPWVLYFn/jGsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}