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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78165cf0551fa91a664dde266ec3d29a32213de48b1b830a9db05e63636fd15f' 
  AND token = 'JLnJDWiJA9eczeZKeN3N8Z6lJwQqSs+aYt7XWQHWBcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}