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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50dedbe515d8d0210d8d9ff69a69048567eb1359a44e156313d65440a74a906e' 
  AND token = 'TikLALjNYiaK73psZwWDIpxYbg/8ThFKypKrBg9vcSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}