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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50bb9efa4d2d0744748a0ccd1977f37f65a1f4aad5341382e39fa7aea4314887' 
  AND token = 'DEMJfU/ruSt8AEdobtUq1xDSI1f8X+R+gEuI292LpZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}