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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ea2cdaf45c0b0023778156946fdf0ab4c640772d21b0c8f433f40a39565b21d' 
  AND token = 'uX8+V1DY5vVrzJCpdt1KIxJnO6zeuQPW7VRA9beACl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}