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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356148a5d734f81924e71391adac2a3e897411b6d853531ec3aef3f4f2c731cb' 
  AND token = 'V4nYW1MARbFzsxnz3anqaDYll4LW1OknSMiWQX9ZRzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}