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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '638ce0725c088682acf740e057b1e31113a7f7b336765c6b77a07df6a9fbe210' 
  AND token = 'YxpimTx4zvtNvRfyOhEz81HJtbySfI+4aYnBwyE7DAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}