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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c3066da58095b4aac383b4170fd43b634b524ec33aaaf1f75ed7957194e8b0b' 
  AND token = '1xDmOO7n9JHtOI6bixuBfJNbDsewzBUiUcqCr/Msf+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}