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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2111f568378c82aef8b8afd6e740aab91445afd2c102ac563b1fe605a6d6a06d' 
  AND token = 'vyCn3rj36eejEXwvsSsRbCmINRpaHUvFujPBpCG+0qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}