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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f4c16ca9716e3b465effb93813ebbfd2215c813821878762e25008dc7f4e3b' 
  AND token = 'b/krD/GVxWjc9iZjxHDHM41caDr6wBz1SvScKbLhvhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}