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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a53caddd4cfe5c8311086c1aae6a144f693dc11a06546fb12272c4a3ec76c3f9' 
  AND token = 'RRoBgkV0/9GwIB/O+sy5QHK73LLM8/xGZ00nUvgA3rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}