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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5875aeee1deddd2f434209d4f1ab653fa7414f6b76d8d1603f7a9fb7bef8b9b' 
  AND token = 'JdWB6+UOI4WybejHhF0rYaxMsVxU9gbV13mDPuLvQMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}