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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728d2aebff29b5256eaa62399c54408b44236336a424ec6e9c7fd33d53de8390' 
  AND token = 'BPLGj92bPeL5qXt9STZU+I3rVw4w6UsEE8qoU4q8R1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}