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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d8fce9abc759928e427b043caea6924794e5c51545c46bc018315fe0f647bd3' 
  AND token = 'DzDWf5yhWMM+ZAYESM9ZXl30SrxRrNrKjYxAoITXLwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00008

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}