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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa84e7532f14c159c9ee83bbca1624550c22062a62b4b7f4e1dd810d5d19b7f6' 
  AND token = 'R2A+Soypu7Zc+4S2vA2TBnpb5HUrmhIctSM2uzO2AqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}