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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a15e1ed621dd79b1cef640319aeb6bd408da6eae88a2abb0c54bdd0c7a6a7e' 
  AND token = '3aJhm6w8BlTTNOl+R0M7OJ1degcPMyW6jv5ZK/v3sZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}