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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc0eb341df16d371238f29a9733f1ff770307837c65debc2fb2d72c8f548f5ce' 
  AND token = 'SPSCV59Im7F/6t0giQrwUmnkA12zNVj9BHORgpHHOvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}