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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2a82b2a4db8f9b9167b03a9502476c2da51d29e9cae6b5fe01586c0fc040b36' 
  AND token = 'BdmRBEQFP1MfRy+L9JWldfuCmK/qwySD2ZyyBwBBKYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}