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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '420784735d7c7401d9ec8a9d65ae724f92316b837670e2e480f851aca4d56045' 
  AND token = 'OS/PXVCN0e/aQhCMtNCZlq2B+U3+0z7o+cyPMJnNPm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}