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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4947a4116daded9f9cf2dfcd4d0ee11b349e0cefed43dfd4225cb916e4480412' 
  AND token = 'qNC4ov1CROeORn5bPn1Q/eV3fQbpQu9CvZcSB3MArBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}