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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1243f03784d956663d16e0c39062421270f660aa9780765422990c00be082103' 
  AND token = 'WUUZ+2C9AT4cMvWx/yPPSQvh7O89II6/8gNkekOr+Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}