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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12640272968a67860ea2e56c80eae490c2e55e8f0c3bb9784b755de3d2547c78' 
  AND token = '+tr1Pw7Tv5l5JgWkJpEhB73B0fm04HaXubD4VR9/sXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}