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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3ac1554f28ec51e96ac14164f7d0289ef140476f7ad1bd0a6497ed403e12581' 
  AND token = 'pPiJ2W/XfZUkICtEPpDS4WZQXptSrVAFZICIRWcndQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}