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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ce7342df45e632f78cb64c56e103f23971381d41a8b8afcc9551e1796b97f34' 
  AND token = 'nEK05i8Yr5fQ7beTm1bdM24UjQ9KX6i11xAiLf0XtFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}