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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12968fce126b82f4f58a43e0b9a1f7fde1345ac64aa848a4b2bc26a01cbcc037' 
  AND token = '1AWjB+Iq4QrI1/5S1wJzZ61sOMMUfDHFXAx7YZlFRm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}