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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1bee4779f73a9b8bdd9d37ea70a9c4f0137d899de7074bd219424e38c750955' 
  AND token = 'wRX1zVH8MzHi3zpvTQQGxx6KAOPK+4tkCLbfX0NPa+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}