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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c90fdb5968f320c76045473c5c5edc59f7fe3cfaff485acd2a85575789a2b0' 
  AND token = 'C04gvCpyJ3Y2t90/+G917IcCCqYEgy+LHc5oHqu+7Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}