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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '501909ffe812d6f36325468f390f3af32cddbaa9905210850f40a1b91087f237' 
  AND token = 'iCbsr3RtTjIk+umNFZ3RxlUG0NUz38ePzzb2hwHszVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}