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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f65f42e000759e99bc7911e0b16326944fb5ced0be666675ea084bdbaf9374e6' 
  AND token = 'NsQOhUuC0YCXfyNtNzcziORhz1URbXp5UVIB/FkO9fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}