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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8ff8022fe90a162bde1f5b5cb4a11e9611fdde007800cfff63e44343be546a9' 
  AND token = 'ioa6isy55cNkzi0zHi8LsdcdzY+64N5nxqwbKXfkTwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}