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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a5d36eaba52cf4ac36e66dbe1646873c4d12e98a710c3f2cbfa3c5d2f910e4' 
  AND token = 'Bw7A66VAg524/stf9MrJJQcMhuIiNbQD+4CLlgqRo6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}