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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc0847263a8b1fb090c229b9112a543153c1d2641119305c2d9170217374691a' 
  AND token = 'dRQY3GuiAHoywmWtaMIIke1i1WmXpaD3aSsYOS1GqM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}