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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3de7f3adafb533593daad570c2f7e091204e17355049abb47ab3dbb9731e5dc2' 
  AND token = 'y5DCbx/0BLUxd0NDnUu90sK7OrpxDRRA3yjK5fB4Irg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}