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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e7e69a1be3f353c90efca844de09f09d00e013bd1c677d31be24cf2e79a3a5b' 
  AND token = 'jNSFEL965P2EDMSJLrPuB3sFTcfPrDbIQhZGvnVoXg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}