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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca0b8e1ccc1d40f03cfaaf2f5593071100b7b7de2cf55730196e358547156aa' 
  AND token = '1+9/UIt6L8AU8Ftb7hAjHgZ3nBZtOcTs27o+BIcPIow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}