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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499fa01ff83486b58a1d99119090cbec331ef09f2f79f13dd3145c0ab615fd7b' 
  AND token = '39WJWGsMVd6i3Ba+uQk7IEE2F9qFoPk6AWHvTS499rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}