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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a226abec4e58d36ffe505b158f8c5e2d5badb2681f3c2efdfa86fcdc2012ae' 
  AND token = 'yKLBMf2zwMUuGdZddfCIplIPgR0dx9Q7k7mVlMVRCUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}