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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52f0d8f29ec32f48683b4072f2762fe21aa2e405808bb846209e07b907c67f74' 
  AND token = '878tT/+SN6ya+zahpg1auIXl1TgYZT9J8ai6Qu5UMzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}