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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad6501348d1ca5a1fd0ddd7712b8f888d1124b4a028fd072ebc925fe7c2ca907' 
  AND token = '7FP7ftDCRFlVZi/aCcEh3FWrf3mSfuWYNnqQJXfL738=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}