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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f2e7933c296d6e61eaa1dc1f3f2c82d25565bd921424b5d8aa0d918d11c4144' 
  AND token = 'uCH/L5ERXY9KMu2aU2gNl2IPckadRHc5JSMWUUy/K2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}