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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6e40a03893aaa9fae9974c33a9687255a9172e31ceaea80861c5380a5200b21' 
  AND token = 'yhmev/YbBrgkWg16TUTBqzBA5fsdNlhqENhNnGsIMco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}